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Zofran Zydis


producent: parallell~~POS=TRUNC import~~POS=HEADCOMP

innehÄller

Zofran Zydis Àr ett lÀkemedel mot illamÄende. Serotoninantagonist.

Aktiva Àmnen

ondansetron


ansökan

Zofran Zydis anvÀnds för behandling av dermatit och krÀkningar i samband med kemoterapi och strÄlbehandling och efter operation.


dos

Finns som lyofiliserade tabletter.

  • Vuxna. Vanligen 8 mg tvĂ„ gĂ„nger om dagen i högst 5 dagar.
  • Barn frĂ„n 6 mĂ„nader. Dosen Ă€r individuell och bestĂ€ms av patientens kroppsytor. Den totala dagsdosen fĂ„r inte överstiga den vuxna dosen.

Obs!

  • Behandling av barn Ă€r en specialistuppgift.
  • Tabletterna ska placeras pĂ„ tungan dĂ€r de löser upp och sedan svaleras med spytten.
  • MĂ€nniskor med uttalad torr mun kan ha svĂ„righeter att anvĂ€nda tabletterna.

Eventuella biverkningar

Mycket vanlig (över 10%)

huvudvÀrk

Vanlig (1-10%)

Rödhet och vÀrme

förstoppning

Mindre vanliga (0,1-1%)

lever~~POS=TRUNC

HjÀrtfrekvensstörningar, lÄngsam hjÀrtfrekvens, lÄgt blodtryck

Biverkningar frÄn muskuloskeletala systemet

SĂ€llsynta (0,01-0,1%)

Inverkan av ekg

Allergiska reaktioner, anafylaktisk chock - ett akut allvarligt allergiskt tillstÄnd

Visuella störningar (t ex dimsyn, frÀmst genom injektion)

Mycket sÀllsynt (mindre Àn 0,01%)

Allvarlig hudreaktion dÀr huden gÄr till marken

ÖvergĂ„ende blindhet (speciellt genom injektion)


Bör inte anvÀndas

  • Bör inte anvĂ€ndas vid överkĂ€nslighet mot nĂ„gon av andreserotonin-antagonisterna.
  • Tabletterna kan innehĂ„lla aspartam, som omvandlas till fenylalanin i organismen. DĂ€rför kan de inte anvĂ€ndas av individer med metaboliska sjukdomar (enzymdefekt som orsakar fenylalanin kan inte brytas ned).

graviditet

Kan endast anvÀndas under vissa förhÄllanden.

amning

Bör inte anvÀndas pÄ grund av bristande kunskap.

trafik

Ingen varning.

givarblod

Falla inte. 7-dagars karantÀn.

effekt

  • Fungerar genom att hĂ€mma effekten av signalsubstansenserotonin i hjĂ€rnan.
  • FrisĂ€ttning av serotonin inducerar eldfasta.
  • Halveringstiden i blodet (TÂœ) Ă€r ungefĂ€r 3 timmar.

farmaceutiska former

Frystorkade tabletter. 1 frystorkad tablett innehÄller 4 mg ondansetron.


SĂ€rskilda varningar

AnvÀnd med försiktighet

  • efter operation av mandlar
  • av överkĂ€nslighet mot andra lĂ€kemedel för illamĂ„ende och krĂ€kningar
  • hos patienter som har eller kan utveckla hjĂ€rtrytmstörningar.

I dÄligt fungerande lever ska dosen inte överstiga 8 mg per dag.


AnvÀndning av andra lÀkemedel

Det Àr viktigt att informera din lÀkare om alla lÀkemedel du tar.
  • Rifampicin (tuberkulos) kan minska effekten av Zofran Zydis.
  • Zofran Zydis kan förstĂ€rka effekten av droger som pĂ„verkar hjĂ€rtans rytm.
  • Samtidig behandling med vissa antidepressiva medel (SSRI-medel) kan utlösa den sĂ„ kallade serotoninsyndrom (t.ex. feber, stelhet, tremor, muskelkramper och förĂ€ndrad mental status). Villkoren kan vara svĂ„r och krĂ€ver snabb medicinsk hjĂ€lp.
  • Samtidig behandling med apomorfin (anti-Parkinsons sjukdom) bör undvikas pĂ„ grund av fall av uttalat blodtrycksfall och förlust av medvetande.

Grants, leverans, förpackning och priser

subventionerutlÀmningDoseringsform och styrkapackningPris i kr.
Kan endast levereras en gÄng efter samma recept, sÄvida inte leveransen sker i flera mindre portioner i tagetlyofiliserade tabletter4 mgEuroPharmaDK10 st. (Blister)UtgÄr 29-01-2018


substitution

frystorkade tabletter 4 mg

Ondansetron "Bluefish" Bluefish Ondansetron

Ondansetron "Orifarm" Orifarm Generics Ondansetron

Ondansetron "Amneal" Amneal Nordiska Ondansetron

ZofranNovartis Ondansetron


Zofran Zydis

FAQ - 💬

❓ How long does Zofran Zydis take to work?

👉 Zofran (ondansetron) begins to work within about 30 minutes. It reaches peak blood concentrations in about 2 hours. Zofran's effects can last 8 to 12 hours. The Zofran dosage varies depending on the severity and cause of the nausea and vomiting.

❓ When should you not use Zofran?

👉 Who should not take Zofran?

  1. low amount of magnesium in the blood.
  2. low amount of potassium in the blood.
  3. extrapyramidal disease, a type of movement disorder.
  4. neuroleptic malignant syndrome, a reaction characterized by fever, muscle rigidity and confusion.
  5. serotonin syndrome, a type of disorder with high serotonin levels.

❓ How do you take Zofran Zydis?

👉 PEEL BACK the foil top of the blister strip and GENTLY remove the Zofran Zydis wafer. (DO NOT try to push it through the foil top as the wafer is fragile and will break up inside the foil). Place the Zofran Zydis wafer on top of your tongue. It will disappear very quickly, then swallow as normal.

❓ How often can you take Zofran wafers?

👉 Adults and children 12 years of age and older—At first, 8 milligrams (mg) taken 30 minutes before starting cancer treatment. The 8-mg dose is taken again 8 hours after the first dose. Then, the dose is 8 mg every 12 hours for 1 to 2 days.

❓ Does Zofran work if you throw up?

👉 Zofran (ondansetron) is used for the prevention of nausea and vomiting. If you're actively vomiting, it will not work to stop you from throwing up. If you continue to vomit after taking Zofran (ondansetron) you should inform your healthcare provider.

❓ Will Zofran make you sleepy?

👉 Zofran may cause headaches, drowsiness, constipation and other mild side effects. In rare cases, the anti-nausea medication can cause erratic heartbeats and high serotonin levels, which may be life-threatening. The drug has also been said to cause birth defects, though research findings are mixed.

❓ Should you take Zofran for stomach bug?

👉 Zofran does not treat the stomach bug directly.” But in stomach bugs where children are experiencing diarrhea, Zofran should be avoided. “Zofran can cause diarrhea and may make diarrhea worse,” Dr. Poinsett says.

❓ Will Zofran help with upset stomach?

👉 Long used for chemotherapy patients battling nausea, the drug was approved in recent years for gastroenteritis, and is generally well tolerated, he said. By stopping vomiting, Zofran can help prevent the dehydration that sometimes requires treatment with IV fluids. "It's been so helpful,'' said Stein.

❓ Does Zofran stop vomiting?

👉 Zofran (ondansetron) is a medication used to prevent nausea and vomiting caused by cancer medications (chemotherapy), radiation therapy, and surgery. Zofran (ondansetron) works by blocking the actions of serotonin, a natural substance in your body, that may cause nausea and vomiting.

❓ Is Zofran used for anxiety?

👉 Zofran (ondansetron) and Compazine (prochlorperazine) are prescribed for the treatment of nausea and vomiting. Zofran is often used to prevent and treat nausea and vomiting during chemotherapy and after surgery. Compazine is also used to treat psychotic disorders such as schizophrenia and anxiety.

❓ Does Zofran help stomach bug?

👉 Long used for chemotherapy patients battling nausea, the drug was approved in recent years for gastroenteritis, and is generally well tolerated, he said. By stopping vomiting, Zofran can help prevent the dehydration that sometimes requires treatment with IV fluids. "It's been so helpful,'' said Stein.

👉 Zofran Zydis Tablet is used for the management of nausea and vomiting induced by cancer treatment through anticancer drugs and radiation in adults and children. It is a prescription medicine. This medicine works by blocking the release of serotonin, a natural substance which may cause vomiting and nausea.

👉 Like other medicines, Zofran Zydis wafers can cause some side effects. If they occur, they are most likely to be minor and temporary. However, some may be serious and need medical attention. The most commonly reported side effects are: dizziness or light-headed feeling. Ask your doctor or pharmacist to answer any questions you may have.

👉 It is not necessary to take Zofran Zydis ODT tablet with water. The typical adult dose of Zofran Zydis is 8 mg of Zofran Zydis 30 minutes before starting radiotherapy or chemotherapy, followed by 8 mg dose 8 hours after the first dose.

👉 ZOFRAN Zydis is a selective 5-HT3 receptor antagonist. While its mechanism of action has not been fully characterized, ondansetron is not a dopamine-receptor antagonist. Serotonin receptors of the 5-HT3 type are present both peripherally on vagal nerve terminals and centrally in the chemoreceptor trigger zone of the area postrema.


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